RRAGB antibody (AA 50-130)

Catalog No. ABIN7218968

The Rabbit Polyclonal anti-RRAGB antibody is suitable to detect RRAGB in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for RRAGB antibody (AA 50-130) (ABIN7218968)

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAGB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RRAGB Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-Rag B Polyclonal Antibody

Specificity: Rag B Polyclonal Antibody detects endogenous levels of Rag B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Rag B at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RRAGB

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Alternative Name: Rag B

Background: RRAGB, Ras-related GTP-binding protein B, Rag B, RagBRas-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.

Gene ID: 10325

UniProt: Q5VZM2