GTR2 antibody (AA 220-300)

Catalog No. ABIN7228816

The Rabbit Polyclonal anti-GTR2 antibody (ABIN7228816) specifically detects GTR2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GTR2 antibody (AA 220-300) (ABIN7228816)

Target: GTR2 (RRAGC) (Ras-Related GTP Binding C (RRAGC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GTR2 Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-GTR2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GTR2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GTR2 protein at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GTR2

Target: GTR2 (RRAGC) (Ras-Related GTP Binding C (RRAGC))

Alternative Name: GTR2

Background: Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2SLC2A2 (Solute Carrier Family 2 Member 2) is a Protein Coding gene. Diseases associated with SLC2A2 include Fanconi-Bickel Syndrome and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Type II diabetes mellitus and Metabolism. SLC2A2 encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in SLC2A2 are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of SLC2A2.

Molecular Weight: 57kD

Gene ID: 6514

UniProt: P11168

Pathways: Autophagy