REC8 antibody (AA 130-210)

Catalog No. ABIN7226198

The Rabbit Polyclonal anti-REC8 antibody is suitable to detect REC8 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for REC8 antibody (AA 130-210) (ABIN7226198)

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-REC8 Antibody

Binding Specificity: AA 130-210

Purpose: Rabbit Anti-Rec8 Polyclonal Antibody

Specificity: Rec8 Polyclonal Antibody detects endogenous levels of Rec8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Rec8 at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for REC8

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Alternative Name: Rec8

Background: REC8, REC8L1, Meiotic recombination protein REC8 homolog, Cohesin Rec8pREC8 (REC8 meiotic recombination protein) encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for REC8.

Molecular Weight: 62kD

Gene ID: 9985

UniProt: O95072