RECQL4 antibody (AA 1030-1110)

Catalog No. ABIN7230986

The Rabbit Polyclonal anti-RECQL4 antibody is suitable to detect RECQL4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for RECQL4 antibody (AA 1030-1110) (ABIN7230986)

Target: RECQL4 (RecQ Protein-Like 4 (RECQL4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RECQL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RECQL4 Antibody

Binding Specificity: AA 1030-1110

Purpose: Rabbit Anti-RECQ4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RECQ4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RECQ4 protein at AA range: 1030-1110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RECQL4

Target: RECQL4 (RecQ Protein-Like 4 (RECQL4))

Alternative Name: RECQ4

Background: ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like type 4, RecQ4, RTS, RecQ protein-like 4The protein encoded by RECQL4 is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. RECQL4 is predominantly expressed in thymus and testis. Mutations in RECQL4 are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.

Molecular Weight: 132kD

Gene ID: 9401

UniProt: O94761

Pathways: Chromatin Binding