RGS20 antibody (AA 180-260)

Catalog No. ABIN7231026

This Rabbit Polyclonal antibody specifically detects RGS20 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for RGS20 antibody (AA 180-260) (ABIN7231026)

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS20 Antibody

Binding Specificity: AA 180-260

Purpose: RGS20 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RGS20 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RGS20 protein at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20

Background: Rabbit Anti-RGS20 Polyclonal Antibody,Regulator of G-protein signaling 20, RGS20, Gz-selective GTPase-activating protein, Gz-GAP, Regulator of G-protein signaling Z1, Regulator of Gz-selective protein signaling 1,The protein encoded by RGS20 (Regulator Of G Protein Signaling 20) belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for RGS20.,RGS20

Molecular Weight: observerd band 42kDa

Gene ID: 8601

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling