RBBP5 antibody (AA 190-270)

Catalog No. ABIN7223946

The Rabbit Polyclonal anti-RBBP5 antibody is suitable to detect RBBP5 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for RBBP5 antibody (AA 190-270) (ABIN7223946)

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RBBP5 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-RBQ-3 Polyclonal Antibody

Specificity: RBQ-3 Polyclonal Antibody detects endogenous levels of RBQ-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human RBQ-3 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RBBP5

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Alternative Name: RBQ-3

Background: RBBP5, RBQ3, Retinoblastoma-binding protein 5, RBBP-5, Retinoblastoma-binding protein RBQ-3RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for RBBP5.

Molecular Weight: 59kD

Gene ID: 5929

UniProt: Q15291