RBBP6 antibody (AA 270-350)

Catalog No. ABIN7230968

This anti-RBBP6 antibody is a Rabbit Polyclonal antibody detecting RBBP6 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for RBBP6 antibody (AA 270-350) (ABIN7230968)

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RBBP6 Antibody

Binding Specificity: AA 270-350

Purpose: RBBP6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RBBP6 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RBBP6 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RBBP6

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Alternative Name: RBBP6

Background: Rabbit Anti-RBBP6 Polyclonal Antibody,E3 ubiquitin-protein ligase RBBP6, Proliferation potential-related protein, Protein P2P-R, RING-type E3 ubiquitin transferase RBBP6, Retinoblastoma-binding Q protein 1, RBQ-1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testis,The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. RBBP6 (RB Binding Protein 6, Ubiquitin Ligase) encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for RBBP6.,RBBP6

Molecular Weight: observerd band 197kDa

Gene ID: 5930

UniProt: Q7Z6E9

Pathways: Regulatory RNA Pathways