RGMB antibody

Catalog No. ABIN7231016

The Rabbit Polyclonal anti-RGMB antibody is suitable to detect RGMB in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for RGMB antibody (ABIN7231016)

Target: RGMB (RGM Domain Family, Member B (RGMB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGMB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGMB Antibody

Purpose: Rabbit Anti-RGMB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RGMB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RGMB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RGMB

Target: RGMB (RGM Domain Family, Member B (RGMB))

Alternative Name: RGMB

Background: RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGONRGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system. RGMB (Repulsive Guidance Molecule Family Member B) is a Protein Coding gene. Diseases associated with RGMB include Basilar Artery Occlusion and Miller-Dieker Lissencephaly Syndrome. Among its related pathways are Netrin-1 signaling and Signaling by BMP.

Molecular Weight: 48kD

Gene ID: 285704

UniProt: Q6NW40