RND2 antibody (AA 140-220)

Catalog No. ABIN7231106

The Rabbit Polyclonal anti-RND2 antibody is suitable to detect RND2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for RND2 antibody (AA 140-220) (ABIN7231106)

Target: RND2 (rho Family GTPase 2 (RND2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RND2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RND2 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-RND2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RND2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RND2 protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RND2

Target: RND2 (rho Family GTPase 2 (RND2))

Alternative Name: RND2

Background: Rho-related GTP-binding protein RhoN, Rho family GTPase 2, Rho-related GTP-binding protein Rho7, Rnd2RND2 (Rho Family GTPase 2) encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. RND2 localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.

Molecular Weight: 24kD

Gene ID: 8153

UniProt: P52198

Pathways: Regulation of Cell Size