ARHGAP4 antibody (AA 890-970)
Quick Overview for ARHGAP4 antibody (AA 890-970) (ABIN7216342)
Target
See all ARHGAP4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 890-970
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Purpose
- p115 Polyclonal Antibody
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Specificity
- P115 Polyclonal Antibody detects endogenous levels of p115 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human p115 at AA range: 890-970
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARHGAP4 (rho GTPase Activating Protein 4 (ARHGAP4))
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Alternative Name
- p115
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Background
- Rabbit Anti-p115 Polyclonal Antibody,USO1, VDP, General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein,USO1 vesicle transport factor encoded by USO1 is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits USO1 vesicle transport factor to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants.,General vesicular transport factor p115
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Molecular Weight
- observerd band 108kDa
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Gene ID
- 8615
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UniProt
- O60763
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size
Target
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