RIMKLA antibody (AA 90-170)

Catalog No. ABIN7214858

This Rabbit Polyclonal antibody specifically detects RIMKLA in WB and ELISA. It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for RIMKLA antibody (AA 90-170) (ABIN7214858)

Target: RIMKLA (Ribosomal Modification Protein RimK-Like Family Member A (RIMKLA))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIMKLA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RIMKLA Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-FAM80A Polyclonal Antibody

Specificity: FAM80A Polyclonal Antibody detects endogenous levels of FAM80A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human FAM80A at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RIMKLA

Target: RIMKLA (Ribosomal Modification Protein RimK-Like Family Member A (RIMKLA))

Alternative Name: FAM80A

Background: RIMKLA, FAM80A, N-acetylaspartyl-glutamate synthetase A, NAAG synthetase A, NAAGS, Ribosomal protein S6 modification-like protein ARIMKLA (N-acetylaspartyl-glutamate synthetase A) is a 391 amino acid protein that belongs to the rimK family. Localizing to cytoplasm, RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit. RIMKLA catalyzes the synthesis of N-acetylaspartyl-glutamate (NAAG). RIMKLA, is almost exclusively expressed in the CNS, whereas RIMKLB, which shares 65 % sequence identity with RIMKLA, is expressed in CNS and testis. It has also been suggested that RIMKLA and RIMKLB also served to ligate free glutamate to (an) acceptor (s). RIMKLA catalyzed the ATP-dependent synthesis of N-acetylaspartylglutamate (NAAG) from N-acetylaspartate and L-glutamate. RIMKLB catalyzed this reaction as well as the synthesis of β-citrylglutamate. The RIMKLA gene is conserved in chimpanzee, dog, cow and mouse, and maps to human chromosome 1p34.2.

Molecular Weight: 43kD

Gene ID: 284716

UniProt: Q8IXN7