The Rabbit Polyclonal anti-RPLP1 antibody (ABIN7231082) specifically detects RPLP1 in WB and ELISA.
The antibody is reactive with Human, Rat and Mouse samples.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
Preservative
ProClin
Precaution of Use
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
RPLP1
(Ribosomal Protein, Large, p1 (RPLP1))
Alternative Name
RLA1
Background
60S acidic ribosomal protein P1, Large ribosomal subunit protein P1RPLP1 (Ribosomal Protein Lateral Stalk Subunit P1) is a Protein Coding gene. Among its related pathways are Viral mRNA Translation and Metabolism. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPLP1 encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E.coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPLP1 dispersed through the genome.