RNF123 antibody

Catalog No. ABIN7231098

This Rabbit Polyclonal antibody specifically detects RNF123 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for RNF123 antibody (ABIN7231098)

Target: RNF123 (Ring Finger Protein 123 (RNF123))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF123 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RNF123 Antibody

Purpose: Rabbit Anti-RN123 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RN123 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RN123 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RNF123

Target: RNF123 (Ring Finger Protein 123 (RNF123))

Alternative Name: RN123

Background: E3 ubiquitin-protein ligase RNF123, Kip1 ubiquitination-promoting complex protein 1, RING finger protein 123, RING-type E3 ubiquitin transferase RNF123The Ring Finger Protein 123 encoded by RNF123 contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. RNF123 (Ring Finger Protein 123) is a Protein Coding gene. Among its related pathways are Deubiquitination and Class I MHC mediated antigen processing and presentation.

Molecular Weight: 144kD

Gene ID: 63891

UniProt: Q5XPI4