SAMHD1 antibody (Internal Region)

Catalog No. ABIN7218500

The Rabbit Polyclonal anti-SAMHD1 antibody is suitable to detect SAMHD1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for SAMHD1 antibody (Internal Region) (ABIN7218500)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SAMHD1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-SAMHD1 Polyclonal Antibody

Specificity: SAMHD1 Polyclonal Antibody detects endogenous levels of SAMHD1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SAMHD1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Background: SAMHD1, MOP5, SAM domain and HD domain-containing protein 1, Dendritic cell-derived IFNG-induced protein, DCIP, Monocyte protein 5, MOP-5SAMHD1 may play a role in regulation of the innate immune response. The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

Molecular Weight: 72kD

Gene ID: 25939

UniProt: Q9Y3Z3