L-Selectin antibody (Internal Region)

Catalog No. ABIN7218272

The Rabbit Polyclonal anti-L-Selectin antibody (ABIN7218272) specifically detects L-Selectin in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for L-Selectin antibody (Internal Region) (ABIN7218272)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L-Selectin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-L-Selectin Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-L-Selectin Polyclonal Antibody

Specificity: L-Selectin Polyclonal Antibody detects endogenous levels of L-Selectin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human L-Selectin

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: L-Selectin

Background: SELL, LNHR, LYAM1, L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62LSELL encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The selectin L contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 42kD

Gene ID: 6402

UniProt: P14151