SFRS6 antibody (AA 30-110)

Catalog No. ABIN7224238

The Rabbit Polyclonal anti-SFRS6 antibody is suitable to detect SFRS6 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for SFRS6 antibody (AA 30-110) (ABIN7224238)

Target: SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SFRS6 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-SRp55 Polyclonal Antibody

Specificity: SRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SRp55 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SFRS6

Target: SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))

Alternative Name: SRp55

Background: SRSF6, SFRS6, SRP55, Serine/arginine-rich splicing factor 6, Pre-mRNA-splicing factor SRP55, Splicing factor, arginine/serine-rich 6The protein encoded by SRSF6 (serine and arginine rich splicing factor 6) is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for SRSF6.

Gene ID: 6431

UniProt: Q13247

Pathways: Ribonucleoprotein Complex Subunit Organization