STK25 antibody (AA 170-250)
Quick Overview for STK25 antibody (AA 170-250) (ABIN7231564)
Target
See all STK25 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 170-250
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Purpose
- Rabbit Anti-STK25 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of STK25 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human STK25 protein at AA range: 170-250
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- STK25 (serine/threonine Kinase 25 (STK25))
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Alternative Name
- STK25
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Background
- Serine/threonine-protein kinase 25, Ste20-like kinase, Sterile 20/oxidant stress-response kinase 1, SOK-1, Ste20/oxidant stress response kinase 1STK25 encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with STK25 is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for STK25.
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Molecular Weight
- 46kD
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Gene ID
- 10494
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UniProt
- O00506
Target
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