PP2BC antibody

Catalog No. ABIN7230740

This Rabbit Polyclonal antibody specifically detects PP2BC in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for PP2BC antibody (ABIN7230740)

Target: PP2BC (Serine/threonine-Protein Phosphatase 2B Catalytic Subunit gamma Isoform (PP2BC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PP2BC antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PP2BC Antibody

Purpose: Rabbit Anti-PP2BC Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PP2BC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PP2BC protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PP2BC

Target: PP2BC (Serine/threonine-Protein Phosphatase 2B Catalytic Subunit gamma Isoform (PP2BC))

Alternative Name: PP2BC

Background: Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoformCalcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by PPP3CC (Protein Phosphatase 3 Catalytic Subunit Gamma) represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for PPP3CC.

Molecular Weight: 56kD

Gene ID: 5533

UniProt: P48454