5HT1B Receptor antibody (AA 180-260)

Catalog No. ABIN7221612

This anti-5HT1B Receptor antibody is a Rabbit Polyclonal antibody detecting 5HT1B Receptor in WB, ELISA, IF and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for 5HT1B Receptor antibody (AA 180-260) (ABIN7221612)

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1B Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-5HT1B Receptor Antibody

Binding Specificity: AA 180-260

Purpose: SR-1B Polyclonal Antibody

Specificity: SR-1B Polyclonal Antibody detects endogenous levels of SR-1B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human SR-1B at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for 5HT1B Receptor

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Alternative Name: SR-1B

Background: Rabbit Anti-SR-1B Polyclonal Antibody,HTR1B, HTR1DB, 5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, S12, Serotonin 1D beta receptor, 5-HT-1D-beta, Serotonin receptor 1B,The 5-hydroxytryptamine receptor 1B encoded by HTR1B is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.,5-hydroxytryptamine receptor 1B

Molecular Weight: observerd band 43kDa

Gene ID: 3351

UniProt: P28222

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins