Serotonin Receptor 3B antibody (AA 140-220)

Catalog No. ABIN7227100

The Rabbit Polyclonal anti-Serotonin Receptor 3B antibody (ABIN7227100) specifically detects Serotonin Receptor 3B in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Serotonin Receptor 3B antibody (AA 140-220) (ABIN7227100)

Target: Serotonin Receptor 3B (HTR3B)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Serotonin Receptor 3B Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-5HT3B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of 5HT3B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human 5HT3B protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Serotonin Receptor 3B

Target: Serotonin Receptor 3B (HTR3B)

Alternative Name: 5HT3B

Background: 5-hydroxytryptamine receptor 3B, 5-HT3-B, 5-HT3B, Serotonin receptor 3BThe product of HTR3B belongs to the ligand-gated ion channel receptor superfamily. HTR3B encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor.

Molecular Weight: 48kD

Gene ID: 9177

UniProt: O95264

Pathways: Synaptic Membrane