SH2D1B antibody (AA 40-120)

Catalog No. ABIN7219370

The Rabbit Polyclonal anti-SH2D1B antibody (ABIN7219370) specifically detects SH2D1B in ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for SH2D1B antibody (AA 40-120) (ABIN7219370)

Target: SH2D1B (SH2 Domain Containing 1B (SH2D1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SH2D1B Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-EAT-2 Polyclonal Antibody

Specificity: EAT-2 Polyclonal Antibody detects endogenous levels of EAT-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human EAT-2 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SH2D1B

Target: SH2D1B (SH2 Domain Containing 1B (SH2D1B))

Alternative Name: EAT-2

Background: SH2D1B, EAT2, SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al. 2001 [PubMed 11689425]).

Gene ID: 117157

UniProt: O14796

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process