SIGLEC9 antibody (Internal Region)

Catalog No. ABIN7218092

This Rabbit Polyclonal antibody specifically detects SIGLEC9 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for SIGLEC9 antibody (Internal Region) (ABIN7218092)

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIGLEC9 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CD329 Polyclonal Antibody

Specificity: CD329 Polyclonal Antibody detects endogenous levels of CD329 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD329

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIGLEC9

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Alternative Name: CD329

Background: SIGLEC8, SAF2, Sialic acid-binding Ig-like lectin 8, Siglec-8, CDw329, Sialoadhesin family member 2, SAF-2, CD329Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e. G. CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13. -q13. and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al. 2000 [PubMed: 11095983]).

Molecular Weight: 50kD

Gene ID: 27181

UniProt: Q9NYZ4