Sideroflexin 4 antibody (AA 1-80)

Catalog No. ABIN7217014

The Rabbit Polyclonal anti-Sideroflexin 4 antibody (ABIN7217014) specifically detects Sideroflexin 4 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Sideroflexin 4 antibody (AA 1-80) (ABIN7217014)

Target: Sideroflexin 4 (SFXN4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sideroflexin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Sideroflexin 4 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-Sideroflexin-4 Polyclonal Antibody

Specificity: Sideroflexin-4 Polyclonal Antibody detects endogenous levels of Sideroflexin-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Sideroflexin-4 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Sideroflexin 4

Target: Sideroflexin 4 (SFXN4)

Alternative Name: Sideroflexin-4

Background: SFXN4, BCRM1, Sideroflexin-4, Breast cancer resistance marker 1SFXN4 encodes a member of the sideroflexin family. The sideroflexin-4 is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene.

Molecular Weight: 37kD

Gene ID: 119559

UniProt: Q6P4A7

Pathways: Transition Metal Ion Homeostasis