SIVA1 antibody

Catalog No. ABIN7231370

This Rabbit Polyclonal antibody specifically detects SIVA1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SIVA1 antibody (ABIN7231370)

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIVA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIVA1 Antibody

Purpose: Rabbit Anti-SIVA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SIVA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SIVA protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIVA1

Target: SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))

Alternative Name: SIVA

Background: Apoptosis regulatory protein Siva, CD27-binding protein, CD27BPSIVA1 (SIVA1 Apoptosis Inducing Factor) encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described. SIVA1 is a Protein Coding gene. Diseases associated with SIVA1 include Scapuloperoneal Myopathy. Among its related pathways are 4-1BB Pathway and p53 Pathway.

Molecular Weight: 19kD

Gene ID: 10572

UniProt: O15304

Pathways: Positive Regulation of Endopeptidase Activity