SIX4 antibody

Catalog No. ABIN7231374

The Rabbit Polyclonal anti-SIX4 antibody is suitable to detect SIX4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for SIX4 antibody (ABIN7231374)

Target: SIX4 (SIX Homeobox 4 (SIX4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIX4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIX4 Antibody

Purpose: Rabbit Anti-SIX4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SIX4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SIX4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIX4

Target: SIX4 (SIX Homeobox 4 (SIX4))

Alternative Name: SIX4

Background: Homeobox protein SIX4, Sine oculis homeobox homolog 4SIX4 (SIX Homeobox 4) is a Protein Coding gene. Diseases associated with SIX4 include Holoprosencephaly 2. Among its related pathways are mir-124 predicted interactions with cell cycle and differentiation and Transcriptional misregulation in cancer. SIX4 encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that SIX4 product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells.

Molecular Weight: 85kD

Gene ID: 51804

UniProt: Q9UIU6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development