SPAG9 antibody (AA 590-670)

Catalog No. ABIN7229214

The Rabbit Polyclonal anti-SPAG9 antibody (ABIN7229214) specifically detects SPAG9 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SPAG9 antibody (AA 590-670) (ABIN7229214)

Target: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SPAG9 Antibody

Binding Specificity: AA 590-670

Purpose: Rabbit Anti-JIP4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of JIP4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human JIP4 protein at AA range: 590-670

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SPAG9

Target: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Alternative Name: JIP4

Background: C-Jun-amino-terminal kinase-interacting protein 4, JIP-4, JNK-interacting protein 4, Cancer/testis antigen 89, CT89, Human lung cancer oncogene 6 protein, HLC-6, HLC-6SPAG9 (Sperm Associated Antigen 9) encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. SPAG9 is a Protein Coding gene. Diseases associated with SPAG9 include Cardiomyopathy, Hypertrophic, 2 and Hodgkin's Lymphoma, Mixed Cellularity. Among its related pathways are Arf6 trafficking events and Akt Signaling.

Molecular Weight: 145kD

Gene ID: 9043

UniProt: O60271

Pathways: Regulation of Muscle Cell Differentiation