SF3A3 antibody

Catalog No. ABIN7231320

This Rabbit Polyclonal antibody specifically detects SF3A3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for SF3A3 antibody (ABIN7231320)

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SF3A3 Antibody

Purpose: SF3A3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SF3A3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SF3A3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Alternative Name: SF3A3

Background: Rabbit Anti-SF3A3 Polyclonal Antibody,Splicing factor 3A subunit 3, SF3a60, Spliceosome-associated protein 61, SAP 61,SF3A3 (Splicing Factor 3a Subunit 3) encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. SF3A3 has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.,SF3A3

Molecular Weight: observerd band 55kDa

Gene ID: 10946

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization