SF3A3 antibody

Catalog No. ABIN7231320

This Rabbit Polyclonal antibody specifically detects SF3A3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for SF3A3 antibody (ABIN7231320)

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SF3A3 Antibody

Purpose: Rabbit Anti-SF3A3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SF3A3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SF3A3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Alternative Name: SF3A3

Background: Splicing factor 3A subunit 3, SF3a60, Spliceosome-associated protein 61, SAP 61SF3A3 (Splicing Factor 3a Subunit 3) encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. SF3A3 has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

Molecular Weight: 55kD

Gene ID: 10946

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization