SCAF1 antibody (AA 10-90)

Catalog No. ABIN7216946

This Rabbit Polyclonal antibody specifically detects SCAF1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for SCAF1 antibody (AA 10-90) (ABIN7216946)

Target: SCAF1 (SR-Related CTD-Associated Factor 1 (SCAF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SCAF1 Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-SCAF1 Polyclonal Antibody

Specificity: SCAF1 Polyclonal Antibody detects endogenous levels of SCAF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human SCAF1 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SCAF1

Target: SCAF1 (SR-Related CTD-Associated Factor 1 (SCAF1))

Alternative Name: SCAF1

Background: SCAF1, SFRS19, SRA1, Splicing factor, arginine/serine-rich 19, SR-related and CTD-associated factor 1, SR-related-CTD-associated factor, SCAF, Serine arginine-rich pre-mRNA splicing factor SR-A1, SR-A1Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex.

Molecular Weight: 140kD

Gene ID: 58506

UniProt: Q9H7N4