SLA antibody

Catalog No. ABIN7231386

The Rabbit Polyclonal anti-SLA antibody (ABIN7231386) specifically detects SLA in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SLA antibody (ABIN7231386)

Target: SLA (Src-Like-Adaptor (SLA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLA Antibody

Purpose: Rabbit Anti-SLAP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SLAP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SLAP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLA

Target: SLA (Src-Like-Adaptor (SLA))

Alternative Name: SLAP1

Background: Src-like-adapter, Src-like-adapter protein 1, SLAP-1, hSLAPSLA (Src Like Adaptor) is a Protein Coding gene. Among its related pathways are EPH-Ephrin signaling and PDGFR-beta signaling pathway. Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.

Molecular Weight: 30kD

Gene ID: 6503

UniProt: Q13239