SRPK1 antibody (AA 490-570)

Catalog No. ABIN7224490

The Rabbit Polyclonal anti-SRPK1 antibody is suitable to detect SRPK1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SRPK1 antibody (AA 490-570) (ABIN7224490)

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRPK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SRPK1 Antibody

Binding Specificity: AA 490-570

Purpose: Rabbit Anti-SRPK1 Polyclonal Antibody

Specificity: SRPK1 Polyclonal Antibody detects endogenous levels of SRPK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SRPK1 at AA range: 490-570

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SRPK1

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Alternative Name: SRPK1

Background: SRPK1, SRSF protein kinase 1, SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1SRPK1 (SRSF protein kinase 1) encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of SRPK1 results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for SRPK1, but their full length nature have not been determined.

Molecular Weight: 95kD

Gene ID: 6732

UniProt: Q96SB4

Pathways: Toll-Like Receptors Cascades