Stanniocalcin 1 antibody

Catalog No. ABIN7231558

The Rabbit Polyclonal anti-Stanniocalcin 1 antibody is suitable to detect Stanniocalcin 1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Stanniocalcin 1 antibody (ABIN7231558)

Target: Stanniocalcin 1 (STC1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Stanniocalcin 1 Antibody

Purpose: Rabbit Anti-STC1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of STC1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human STC1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Stanniocalcin 1

Target: Stanniocalcin 1 (STC1)

Alternative Name: STC1

Background: Stanniocalcin-1STC1 encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. STC1 contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. STC1 has altered expression in hepatocellular, ovarian, and breast cancers.

Molecular Weight: 27kD

Gene ID: 6781

UniProt: P52823

Pathways: Hormone Activity