SMC1B antibody (AA 110-190)

Catalog No. ABIN7231408

The Rabbit Polyclonal anti-SMC1B antibody (ABIN7231408) specifically detects SMC1B in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for SMC1B antibody (AA 110-190) (ABIN7231408)

Target: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMC1B Antibody

Binding Specificity: AA 110-190

Purpose: SMC1B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SMC1B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SMC1B protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SMC1B

Target: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Alternative Name: SMC1B

Background: Rabbit Anti-SMC1B Polyclonal Antibody,Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B,SMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).,SMC1B

Molecular Weight: observerd band 135kDa

Gene ID: 27127

UniProt: Q8NDV3