SMC1B antibody (AA 954-1060) (Biotin)

Catalog No. ABIN7170859

Product Details anti-SMC1B Antibody (Biotin)

Target: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Binding Specificity: AA 954-1060

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC1B antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Structural maintenance of chromosomes protein 1B protein (954-1060AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMC1B

Target: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Alternative Name: SMC1B (SMC1B Products)

Synonyms: SMC1BETA antibody, SMC1L2 antibody, bK268H5 antibody, bK268H5.5 antibody, SMC-1B antibody, SMC1beta antibody, Smc1l2 antibody, structural maintenance of chromosomes 1B antibody, SMC1B antibody, Smc1b antibody

Background:

Background: Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).

Aliases: bK268H5 antibody, SMC protein 1B antibody, SMC-1-beta antibody, SMC-1B antibody, SMC1 beta antibody, SMC1B antibody, SMC1B_HUMAN antibody, SMC1beta antibody, SMC1beta protein antibody, Smc1l2 antibody, Structural maintenance of chromosomes 1-like 2 antibody, Structural maintenance of chromosomes 1B antibody, Structural maintenance of chromosomes protein 1B antibody

UniProt: Q8NDV3