Synapsin III antibody

Catalog No. ABIN7231616

This anti-Synapsin III antibody is a Rabbit Polyclonal antibody detecting Synapsin III in WB and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for Synapsin III antibody (ABIN7231616)

Target: Synapsin III (SYN3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synapsin III antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Synapsin III Antibody

Purpose: SYN3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SYN3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SYN3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Synapsin III

Target: Synapsin III (SYN3)

Alternative Name: SYN3

Background: Rabbit Anti-SYN3 Polyclonal Antibody,Synapsin-3, Synapsin III,SYN3 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by SYN3 shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12. , a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of SYN3 and is transcribed in the opposite direction. Alternative splicing of SYN3 results in multiple splice variants that encode different isoforms.,SYN3

Molecular Weight: observerd band 63kDa

Gene ID: 8224

UniProt: O14994