SV2B antibody

Catalog No. ABIN7231600

The Rabbit Polyclonal anti-SV2B antibody (ABIN7231600) specifically detects SV2B in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SV2B antibody (ABIN7231600)

Target: SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SV2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SV2B Antibody

Purpose: Rabbit Anti-SV2B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SV2B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SV2B protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SV2B

Target: SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))

Alternative Name: SV2B

Background: Synaptic vesicle glycoprotein 2BSV2B encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. SV2B shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients.

Molecular Weight: 75kD

Gene ID: 9899

UniProt: Q7L1I2