SYT2 antibody (AA 40-120)

Catalog No. ABIN7231626

The Rabbit Polyclonal anti-SYT2 antibody (ABIN7231626) specifically detects SYT2 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SYT2 antibody (AA 40-120) (ABIN7231626)

Target: SYT2 (Synaptotagmin II (SYT2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SYT2 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-SYT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SYT2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SYT2 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SYT2

Target: SYT2 (Synaptotagmin II (SYT2))

Alternative Name: SYT2

Background: Synaptotagmin-2, Synaptotagmin II, SytIISYT2 (Synaptotagmin 2) is a Protein Coding gene. Diseases associated with SYT2 include Myasthenic Syndrome, Congenital, 7, Presynaptic and Syt2-Related Congenital Myasthenic Syndrome. Among its related pathways are HIV Life Cycle and Uptake and actions of bacterial toxins. SYT2 encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in SYT2 are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants.

Molecular Weight: 46kD

Gene ID: 127833

UniProt: Q8N9I0

Pathways: Synaptic Vesicle Exocytosis