The Rabbit Polyclonal anti-SYT8 antibody (ABIN7231636) specifically detects SYT8 in WB and ELISA.
The antibody is reactive with Human, Mouse and Rat samples.
SYT8
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
Preservative
ProClin
Precaution of Use
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
SYT8
(Synaptotagmin VIII (SYT8))
Alternative Name
SYT8
Background
Synaptotagmin-8, Synaptotagmin VIII, SytVIIISYT8 (Synaptotagmin 8) encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away. This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.