SYT12 antibody

Catalog No. ABIN7231620

The Rabbit Polyclonal anti-SYT12 antibody (ABIN7231620) specifically detects SYT12 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SYT12 antibody (ABIN7231620)

Target: SYT12 (Synaptotagmin XII (SYT12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SYT12 Antibody

Purpose: Rabbit Anti-SYT12 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SYT12 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SYT12 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SYT12

Target: SYT12 (Synaptotagmin XII (SYT12))

Alternative Name: SYT12

Background: Synaptotagmin-12, Synaptotagmin XII, SytXIISYT12 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. SYT12 has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.

Molecular Weight: 46kD

Gene ID: 91683

UniProt: Q8IV01