SYTL4 antibody (AA 350-430)

Catalog No. ABIN7225970

The Rabbit Polyclonal anti-SYTL4 antibody is suitable to detect SYTL4 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for SYTL4 antibody (AA 350-430) (ABIN7225970)

Target: SYTL4 (Synaptotagmin-Like 4 (SYTL4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYTL4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SYTL4 Antibody

Binding Specificity: AA 350-430

Purpose: Rabbit Anti-Granuphilin Polyclonal Antibody

Specificity: Granuphilin Polyclonal Antibody detects endogenous levels of Granuphilin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Granuphilin at AA range: 350-430

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SYTL4

Target: SYTL4 (Synaptotagmin-Like 4 (SYTL4))

Alternative Name: Granuphilin

Background: SYTL4, Synaptotagmin-like protein 4, Exophilin-2, GranuphilinSYTL4 (synaptotagmin like 4) encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.

Molecular Weight: 76kD

Gene ID: 94121

UniProt: Q96C24

Pathways: Negative Regulation of Hormone Secretion