TCP1 alpha/CCTA antibody (Internal Region)

Catalog No. ABIN7224630

This Rabbit Polyclonal antibody specifically detects TCP1 alpha/CCTA in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TCP1 alpha/CCTA antibody (Internal Region) (ABIN7224630)

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCP1 alpha/CCTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TCP1 alpha/CCTA Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-TCP-1 α Polyclonal Antibody

Specificity: TCP-1 α Polyclonal Antibody detects endogenous levels of TCP-1 α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TCP-1 alpha

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TCP1 alpha/CCTA

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Alternative Name: TCP-1 alpha

Background: TCP1, CCT1, CCTA, T-complex protein 1 subunit alpha, TCP-1-alpha, CCT-alphaThe protein encoded by TCP1 (t-complex 1) is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of TCP1, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from TCP1 have been found.

Molecular Weight: 60kD

Gene ID: 6950

UniProt: P17987