TACR1 antibody (AA 180-260)

Catalog No. ABIN7224586

The Rabbit Polyclonal anti-TACR1 antibody (ABIN7224586) specifically detects TACR1 in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for TACR1 antibody (AA 180-260) (ABIN7224586)

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TACR1 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-NK-1R Polyclonal Antibody

Specificity: NK-1R Polyclonal Antibody detects endogenous levels of NK-1R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NK-1R at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Alternative Name: NK-1R

Background: TACR1, NK1R, TAC1R, Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1TACR1 (tachykinin receptor 1) belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. TACR1 encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Molecular Weight: 50kD

Gene ID: 6869

UniProt: P25103

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration