TACR2 antibody (AA 270-350)

Catalog No. ABIN7224576

This Rabbit Polyclonal antibody specifically detects TACR2 in WB, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for TACR2 antibody (AA 270-350) (ABIN7224576)

Target: TACR2 (Tachykinin Receptor 2 (TACR2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TACR2 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-NK-2R Polyclonal Antibody

Specificity: NK-2R Polyclonal Antibody detects endogenous levels of NK-2R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human NK-2R at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TACR2

Target: TACR2 (Tachykinin Receptor 2 (TACR2))

Alternative Name: NK-2R

Background: TACR2, NK2R, NKNAR, TAC2R, Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2TACR2 (tachykinin receptor 2) belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. TACR2 encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.

Molecular Weight: 48kD

Gene ID: 6865

UniProt: P21452

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion