TAZ antibody (Internal Region)

Catalog No. ABIN7224612

The Rabbit Polyclonal anti-TAZ antibody is suitable to detect TAZ in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for TAZ antibody (Internal Region) (ABIN7224612)

Target: TAZ (Tafazzin (TAZ))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TAZ Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Tafazzin Polyclonal Antibody

Specificity: Tafazzin Polyclonal Antibody detects endogenous levels of Tafazzin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Tafazzin

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TAZ

Target: TAZ (Tafazzin (TAZ))

Alternative Name: Tafazzin

Background: TAZ, EFE2, G4.5, Tafazzin, Protein G4.5TAZ (tafazzin) encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in TAZ have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced, the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Molecular Weight: 33kD

Gene ID: 6901

UniProt: Q16635