TNXB antibody (AA 1730-1810)

Catalog No. ABIN7224736

The Rabbit Polyclonal anti-TNXB antibody (ABIN7224736) specifically detects TNXB in IHC, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for TNXB antibody (AA 1730-1810) (ABIN7224736)

Target: TNXB (Tenascin XB (TNXB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNXB antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TNXB Antibody

Binding Specificity: AA 1730-1810

Purpose: Rabbit Anti-Tenascin-X Polyclonal Antibody

Specificity: Tenascin-X Polyclonal Antibody detects endogenous levels of Tenascin-X protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Tenascin-X at AA range: 1730-1810

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TNXB

Target: TNXB (Tenascin XB (TNXB))

Alternative Name: Tenascin-X

Background: TNXB, HXBL, TNX, TNXB1, TNXB2, XB, Tenascin-X, TN-X, Hexabrachion-like proteinTNXB (tenascin XB) encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. TNXB localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of TNXB is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for TNXB.

Gene ID: 7148

UniProt: P22105