Tensin 1 antibody (pTyr1326)

Catalog No. ABIN7213348

This Rabbit Polyclonal antibody specifically detects Tensin 1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Tensin 1 antibody (pTyr1326) (ABIN7213348)

Target: Tensin 1 (TNS1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tensin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Tensin 1 Antibody

Binding Specificity: pTyr1326

Purpose: Rabbit Anti-Tensin-1 (phospho Tyr1326) Polyclonal Antibody

Specificity: Phospho-Tensin-1 (Y1326) Polyclonal Antibody detects endogenous levels of Tensin-1 protein only when phosphorylated at Y1326.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Tensin-1 Phospho-Tyr1326

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Tensin 1

Target: Tensin 1 (TNS1)

Alternative Name: Tensin-1

Background: TNS1, TNS, Tensin-1Tensin 1 encoded by TNS1 localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. Tensin 1 is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 185kD

Gene ID: 7145

UniProt: Q9HBL0