TUT1 antibody (AA 260-340)

Catalog No. ABIN7224322

The Rabbit Polyclonal anti-TUT1 antibody (ABIN7224322) specifically detects TUT1 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TUT1 antibody (AA 260-340) (ABIN7224322)

Target: TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TUT1 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-TUTase Polyclonal Antibody

Specificity: TUTase Polyclonal Antibody detects endogenous levels of TUTase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TUTase at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TUT1

Target: TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))

Alternative Name: TUTase

Background: TUT1, RBM21, Speckle targeted PIP5K1A-regulated poly(A) polymerase, Star-PAP, RNA-binding motif protein 21, RNA-binding protein 21, U6 snRNA-specific terminal uridylyltransferase 1, U6-TUTaseTUT1 (terminal uridylyl transferase 1, U6 snRNA-specific) encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly (A) polymerase. The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.

Molecular Weight: 95kD

Gene ID: 64852

UniProt: Q9H6E5