CD37 antibody (Internal Region)

Catalog No. ABIN7218444

The Rabbit Polyclonal anti-CD37 antibody is suitable to detect CD37 in samples from Human, Mouse and Rat. It has been validated for ELISA, IF, WB and IHC.

Quick Overview for CD37 antibody (Internal Region) (ABIN7218444)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD37 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CD37 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CD37 Polyclonal Antibody

Specificity: CD37 Polyclonal Antibody detects endogenous levels of CD37 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD37

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background: CD37, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37CD37 Molecule encoded by CD37 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 30kD

Gene ID: 951

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response