Tetraspanin 7 antibody (AA 101-150)

Catalog No. ABIN7227712

This Rabbit Polyclonal antibody specifically detects Tetraspanin 7 in ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Tetraspanin 7 antibody (AA 101-150) (ABIN7227712)

Target: Tetraspanin 7 (TSPAN7)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tetraspanin 7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Tetraspanin 7 Antibody

Binding Specificity: AA 101-150

Purpose: CD231 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD231

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CD231 protein at AA range: 101-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Tetraspanin 7

Target: Tetraspanin 7 (TSPAN7)

Alternative Name: CD231

Background: Rabbit Anti-CD231 Polyclonal Antibody,Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD antigen CD231,The protein encoded by TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TSPAN7 is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TSPAN7 (Tetraspanin 7) is a Protein Coding gene. Diseases associated with TSPAN7 include X-Linked Non-Specific Intellectual Disability and Miliaria Rubra. Among its related pathways are Cell surface interactions at the vascular wall and Response to elevated platelet cytosolic Ca2+. An important paralog of TSPAN7 is ENSG00000250349.,CD231

Gene ID: 7102

UniProt: P41732