Thimet Oligopeptidase 1 antibody

Catalog No. ABIN7231786

This anti-Thimet Oligopeptidase 1 antibody is a Rabbit Polyclonal antibody detecting Thimet Oligopeptidase 1 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Thimet Oligopeptidase 1 antibody (ABIN7231786)

Target: Thimet Oligopeptidase 1 (THOP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Thimet Oligopeptidase 1 Antibody

Purpose: THOP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of THOP1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human THOP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: THOP1

Background: Rabbit Anti-THOP1 Polyclonal Antibody,Thimet oligopeptidase, Endopeptidase 24.15, MP78,Thimet Oligopeptidase 1 encoded by THOP1 is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. Thimet Oligopeptidase 1 also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. THOP1 (Thimet Oligopeptidase 1) is a Protein Coding gene. Among its related pathways are African trypanosomiasis and ACE Inhibitor Pathway, Pharmacodynamics.,THOP1

Molecular Weight: observerd band 75kDa

Gene ID: 7064

UniProt: P52888